Metal oxide nanomaterials have been widely applied in the high-performance gas sensors. However, compared with n-type metal oxides, p-type semiconductor nanomaterials have been relatively less studied for gas sensing applications. In this work, CuO nanoplates were synthesized by a facile hydrothermal route at different temperatures without using any surfactant to study the effect on the gas sensing properties of materials, works based on the resistance change. The morphologies and crystal structures of the synthesized materials were characterized by filed-emission scanning electron microcopy (FE-SEM) and X-ray diffraction (XRD). Gas sensing characteristics were measured at various concentrations of H2 from 50-1000 ppm at 250 – 400 oC. Results demonstrated that the synthesized CuO nanoplates exhibited p-type semiconducting behavior, where the sensor resistance increased upon exposure to H2. Finally, a sensing mechanism for the gas sensing behavior of CuO nanoplates was also proposed.