Rambutan (Nephelium lappaceum L.) is a fruit tropical tree in the family Sapindaceae. In canned food processing, rambutan peels are discarded as waste. Recently studies show that rambutan peels can be used as a material sources which contain abundant bioactive substances.The present study investigates some compounds from the ethanolic extract of rambutan (Nephelium lappaceum L.) rind, harvested in Đong Nai province. Four compounds: (-)-Shikimic acid (1), (-)-3-epi-shikimic acid (2), vitexin (3) and (-)-epicatechin (4) were isolated by column chromatography. Their structures were elucidated by analysis of mass spectra (MS), nuclear magnetic resonance (NMR) spectra and comparison with the published data.