Porous hydroxyapatite scaffold (PHS) was fabricated by replica method, where polyurethane foam has filaments coated with a HAp suspension. A subsequent thermal treatment removed the organic materials, remaining the HAp ceramic in the substratum. And then, microwave processing of the PHS was investigated in a dual frequency microwave sintering furnace. Through the optimization of sintering conditions, such as the sintering temperature and holding time, the microstructure and material properties of the PHS were investigated such as pore sizes, grain size, relative density, compressive strength. The obtained results were compared to those of the conventional sintering process and also revealed that microwave processing was a promising method to fabricate PHS for tissue engineering application. On the other hand, nano-Ag, which was used as antibacterial effect to prevent infections, spot-coated PHS was successfully synthesized by the electroless deposition process. The results showed that nano-Ag spots were homogeneously dispersed on the PHS