RESEARCH ON APPLYING MOLECULARLY IMPRINTED POLYMER TECHNIQUE IN FABRICATION OF ARTIFICIAL BIORECEPTOR FOR CHLOAMPHENICOL DETECHTION

Authors: Phí Văn Toàn*, Trương Thị Ngọc Liên, Nguyễn Quốc Hảo

Abstract

In this paper we present our research on the development of impedimetric sensor for Chloramphenicol (CAP) detection by using artificial bioreceptor MIP. Our results show that fabricated sensor has high selectivity and low detection limit (LOD = 3,67 nM). Furthermore, the process for sensor fabrication has low cost as cheap screen-printed carbon ink electrode but possesses many advantages of possibility for using Au-printed electrode, simple measurement method, short fabrication time and good reproducibility. Besides, based on current study, it was found that EIS is an impressive method for monitoring the rebinding of target molecules with their surrounding polymer matrix that occurred on the electrode surface. The sensor platform could be easily applied for detection of other small proteins, with selection of the detection platform based on the desired for sensitivity.

Keyword

MIP, AuNPs, Chloramphenicol
Pages : 74-78

Related Articles:

Authors : Lê Minh Tân, Trần Thu Thuỷ, Vũ Duy Đạt, Cao Xuân Trường, Nguyễn Đình Hữu Đức, Trần Thiên Đức*
Authors : Nguyễn Quốc Minh*, Võ Tá Đông, Nguyễn Duy Minh
Authors : Vũ Văn Trọng, Trương Thị Hồng Ngọc, Lê Quân, Vũ Văn Huy, Bùi Thanh Duy, Nguyễn Lê Huy*, Nguyễn Vân Anh, Nguyễn Tuấn Dung
Authors : Lưu Thị Lan Anh*, Nguyễn Ngọc Trung
Authors : Mạc Thị Bích *, Phạm Thị Hoa , Bành Tiến Long , Nguyễn Đức Toàn *
Authors : Nguyễn Ngọc Thắng*, Phạm Thị Ngọc , Vũ Tiến Hiếu, Bùi Văn Huấn