Stibenoids from Gnetum montanum Markgr. in Vietnam ☆

Gnetum montanum Markgr.(Gnetaceae), Vietnamese name as Day gam, Gam nui is creeping and turning wood, distributed in natural forests at altitudes of 200-1200 m. It grows widely in mountainous areas in Vietnam. Its stem can disinfect, eliminate rheumatism, eliminate toxins in the body, and support the treatment of inflammation, blood disorders, leprosy, or joint pain in traditional medicine. In the course of study on the chemical composition of Gnetum montanum Markgr. in Vietnam, this paper described the extraction and structure evaluation of four compounds, including lehmbachol D (1), 3,4,5-trimethoxy-10,14-stibenediol (2), gnetucleistol C (3) and (+)-pinoresinol (4). The stems of this plant were collected, identified, dried and extracted in different polarity solvents. These substances were isolated from the ethyl acetate of methanol extract on the basis of column chromatography combined with thin layer chromatography. Their structures were identified based on spectroscopic evaluation and comparison of corresponding authentic compounds. Compound 2 was firstly recorded on the paper.